Inhibitory Effects of Ischemic Preconditioning on Occlusion-induced Arrhythmias and Reperfusion-induced Arrhythmias in Anesthetized Rats.
نویسندگان
چکیده
منابع مشابه
Effects of ischemic preconditioning on ischemia/reperfusion-induced arrhythmias by upregulatation of connexin 43 expression
BACKGROUND The susceptibility of hypertrophied myocardium to ischemia-reperfusion injury is associated with increased risk of postoperative arrhythmias. We investigate the effects of ischemic preconditioning (IP) on post-ischemic reperfusion arrhythmias in hypertrophic rabbit hearts. METHODS Thirty-three rabbit models of myocardial hypertrophy were randomly divided into three groups of 11 eac...
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BACKGROUND 5-Lipoxygenase is an enzyme involved in the synthesis of leukotriene eicosanoids from arachidonic acid. The therapeutic potential of zileuton, an inhibitor of 5-lipoxygenase, and montelukast, a cysteinyl leukotriene receptor antagonist, for the treatment of ischemia/reperfusion (I/R) injury of the heart has been proposed in a few studies. However, the effects of zileuton and monteluk...
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BACKGROUND Hyperoxic preconditioning is known to protect the heart against necrosis and contractile dysfunction, but protection against arrhythmias has not been well characterized. OBJECTIVE The authors hypothesized that pre-exposure to normobaric hyperoxia (H) reduces ischemia and reperfusion-induced arrhythmias in isolated rat hearts. METHODS Following 60 and 180 min of hyperoxia treatmen...
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15 صفحه اولSuppression of ischemic and reperfusion ventricular arrhythmias by inhalational anesthetic-induced preconditioning in the rat heart.
Inhalational anesthetic-induced preconditioning (APC) has been shown to reduce infarct size and attenuate contractile dysfunction caused by myocardial ischemia. Only a few studies have reported the effects of APC on arrhythmias during myocardial ischemia-reperfusion injury, focusing exclusively on reperfusion. Accordingly, the aim of the present study was to examine the influence of APC on vent...
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ژورنال
عنوان ژورنال: Japanese Journal of Electrocardiology
سال: 1997
ISSN: 1884-2437,0285-1660
DOI: 10.5105/jse.17.133